Pre-and-post menopause vaginal conditions

Pre-and-post menopause vaginal conditions:

Atrophic changes, before, during and after menopause due to declining estrogen levels can result in a range of symptoms, including vaginal dryness and irritation as well as increased susceptibility to vaginal trauma and infection.
StrataMGT has been developed for use on all types of mucosal conditions and post-procedure care where the epidermis of the vaginal mucosa is damaged or wounded including:

  • Vaginal atrophy and vaginal dryness
  • Vulvovaginitis
  • Vulvodynia

Vaginal Atrophy:​

Vaginal Atrophy (VA), atrophic vaginitis, or urogenital atrophy has also a relatively new term for the condition known as Genitourinary Syndrome of Menopause (GSM). (8)
VA is a chronic and progressive condition where the lining of the vagina gets drier and thinner, leading to symptoms such as itching, burning and pain during intercourse, among other symptoms. 

  • Vaginal Atrophy affects 40%-57% of postmenopausal women with some reports showing a prevalence up to 90%. (9,10)
  • Even though the condition mainly affects postmenopausal women, 15% of the female population experiences symptoms of VA before menopause. (8)
  • Patients affected by breast cancer present menopausal symptoms following chemotherapy or aromatase inhibitor treatments. (9)

Vulvovaginitis:​

Vulvovaginitis is a common problem. It usually presents with itching and vaginal discharge. The likely causes differ in girls, women and postmenopausal women. Most women will experience at least one episode in their lifetime. The symptoms of vulvovaginitis include discharge, itch, pain, odor, dysuria and dyspareunia.
Common causes include candidiasis, bacterial vaginosis and skin diseases affecting the vulva. (23)

Vulvodynia:​

Vulvodynia is a chronic painful disorder with an estimated prevalence of 9-12%. A rising incidence of the condition constitutes a growing problem.
The pain often is described as “burning”, but it may be irritating, sharp, prickly, or, occasionally, pruritic, and it can be mild to severe. (24)

Current treatment options for Vaginal Atrophy:

Certain lubricants and moisturizers are not ideal because they may interfere with the healing process, cause irritation, or increase the risk for contact dermatitis. (28)

Hormonal therapy offers significant benefits for treating VA, but it is also important to be aware of possible side effects, such as an increased risk of heart disease, breast cancer, thromboembolic complications, and cerebrovascular diseases. (7,16)

Phytoestrogens could provide temporary relief of symptoms; however, there is insufficient clinical data and limited efficacy. (7,16)


The American College of Obstetricians and Gynecologists (ACOG) and the American Society of Clinical Oncology (ASCO), recommend the use of non-hormonal options as the first choice for treatment of VA in women with current or a history of estrogen-dependent breast cancer. (9,17)

More Women's Health Resources

Here is a selection of sources and references that are useful for all the women who would like to know more about the causes, side effects and symptoms of menopause:

  • American College of Obstetricians and Gynecologists (ACOG): ACOG is a leading professional association of obstetricians and gynecologists. They provide resources, guidelines, and information related to women’s reproductive health. 
    Link: Resources for You | ACOG

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